Etudes, Recherche et Publications

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Expérience en études cliniques

Investigateur principal et co- investigateur de plusieurs études dans les domaines des maladies pulmonaires rares, mucoviscidose et transplantation pulmonaire, infectiologie pulmonaire.
Investigateur coordonnateur national de l'étude HIT CF Project, 2019

Publications des 5 dernières années

Adherence, reliability, and variability of home spirometry telemonitoring in cystic fibrosis. Beaufils F, Enaud R, Gallode F, Boucher G, Macey J, Berger P, Fayon M, Bui S. Front Pediatr. 2023 Feb 23;11:1111088
The French Compassionate Program of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis with advanced lung disease and no F508del CFTR variant. Burgel PR, Sermet-Gaudelus I, Durieu I, Kanaan R, Macey J, Grenet D, Porzio M, Coolen-Allou N, Chiron R, Marguet C, Douvry B, Dufeu N, Danner-Boucher I, Foucaud P, Lemonnier L, Girodon E, Da Silva J, Martin C; French CF Reference Network study group. Eur Respir J. 2023 Feb 16:2202437
ROHHAD syndrome without rapid-onset obesity: A diagnosis challenge. Desse B, Tran A, Butori M, Marchal S, Afanetti M, Barthélemy S, Bérard E, Baechler E, Debelleix S, Lampin ME, Macey J, Massenavette B, Harvengt J, Trang H, Giovannini-Chami L. Front Pediatr. 2022 Aug 31;10:910099
Safety and pharmacokinetics of Roscovitine (Seliciclib) in cystic fibrosis patients chronically infected with Pseudomonas aeruginosa, a randomized, placebo-controlled study. Meijer L, Hery-Arnaud G, Leven C, Nowak E, Hillion S, Renaudineau Y, Durieu I, Chiron R, Prevotat A, Fajac I, Hubert D, Murris-Espin M, Huge S, Danner-Boucher I, Ravoninjatovo B, Leroy S, Macey J, Urban T, Rault G, Mottier D, Berre RL. J Cyst Fibros. 2022 May;21(3):529-536
Chronic lung allograft dysfunction is associated with an early increase of circulating cytotoxic CD4+CD57+ILT2+ T cells, selectively inhibited by the immune check-point HLA-G. Brugière O, Mouren
D, Trichereau J, Vallée A, Kuzniak I, Hirschi S, Renaud-Picard B, Reynaud-Gaubert M, Nieves A, Bunel V, Messika J, Demant X, Macey J, Le Pavec J, Dauriat G, Saint-Raymond C, Falque L, Mornex JF, Tissot A, Foureau A, Borgne Krams AL, Bousseau V, Magnan A, Picard C, Roux A, Carosella E, LeMaoult J, Rouas-Freiss N; COLT Consortium. J Heart Lung Transplant. 2022 May;41(5):626-640
Cumulative Incidence and Risk Factors for Severe COVID-19 in French People with Cystic Fibrosis.
Corvol H, de Miranda S, Dehillotte C, Lemonnier L, Chiron R, Danner-Boucher I, Hamidfar R, Houdouin V, Macey J, Marguet C, Murris-Espin M, Reynaud Q, Reix P, Gaubert MR, Kemgang A, Burgel PR; French Cystic Fibrosis Reference Network study group. Clin Infect Dis. 2022 Apr 27:ciac333
Artificial intelligence in computed tomography for quantifying lung changes in the era of CFTR modulators. Dournes G, Hall CS, Willmering MM, Brody AS, Macey J, Bui S, Denis de Senneville B, Berger P, Laurent F, Benlala I, Woods JC. Eur Respir J. 2022 Mar 3;59(3):2100844
Rapid Improvement after Starting Elexacaftor-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease. Burgel PR, Durieu I, Chiron R, Ramel S, Danner-Boucher I, Prevotat A, Grenet D, Marguet C, Reynaud-Gaubert M, Macey J, Mely L, Fanton A, Quetant S, Lemonnier L, Paillasseur JL, Da Silva J, Martin C; French Cystic Fibrosis Reference Network Study Group. Am J Respir Crit Care Med. 2021 Jul 1;204(1):64-73
The Clinical Use of Lung MRI in Cystic Fibrosis: What, Now, How? Dournes G, Walkup LL, Benlala I, Willmering MM, Macey J, Bui S, Laurent F, Woods JC. Chest. 2021 Jun;159(6):2205-2217
Quantification of MRI T2 Interstitial Lung Disease Signal-Intensity Volume in Idiopathic Pulmonary Fibrosis: A Pilot Study. Benlala I, Albat A, Blanchard E, Macey J, Raherison C, Benkert T, Berger P, Laurent F, Dournes G. J Magn Reson Imaging. 2021 May;53(5):1500-1507
Allergic Broncho-Pulmonary Aspergillosis (ABPA) in cystic fibrosis: Mechanisms, diagnosis and therapeutic options. Bui S, Dournes G, Fayon M, Bouchet S, Burgel PR, Macey J, Murris M, Delhaes L. Rev Mal Respir. 2021 May;38(5):466-476
Clinical response to lumacaftor-ivacaftor in patients with cystic fibrosis according to baseline lung function. Burgel PR, Durieu I, Chiron R, Mely L, Prevotat A, Murris-Espin M, Porzio M, Abely M, Reix P, Marguet C, Macey J, Sermet-Gaudelus I, Corvol H, Bui S, Biouhee T, Hubert D, Munck A, Lemonnier L, Dehillotte C, Silva JD, Paillasseur JL, Martin C; French Cystic Fibrosis Reference Network study group. J Cyst Fibros. 2021 Mar;20(2):220-227
Volumetric quantification of lung MR signal intensities using ultrashort TE as an automated score in cystic fibrosis. Benlala I, Point S, Leung C, Berger P, Woods JC, Raherison C, Laurent F, Macey J, Dournes G. Eur Radiol. 2020 Oct;30(10):5479-5488
Management of initial colonisations with Burkholderia species in France, with retrospective analysis in five cystic fibrosis Centres: a pilot study. Gruzelle V, Guet-Revillet H, Segonds C, Bui S, Macey J, Chiron R, Michelet M, Murris-Espin M, Mittaine M. BMC Pulm Med. 2020 Jun 5;20(1):159
Real-Life Safety and Effectiveness of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis. Burgel PR, Munck A, Durieu I, Chiron R, Mely L, Prevotat A, Murris-Espin M, Porzio M, Abely M, Reix P, Marguet C, Macey J, Sermet-Gaudelus I, Corvol H, Bui S, Lemonnier L, Dehilotte C, Da Silva J, Paillasseur JL, Hubert D; French Cystic Fibrosis Reference Network study group. Am J Respir Crit Care Med. 2020 Jan 15;201(2):188-197
Quantification of MRI T2-weighted High Signal Volume in Cystic Fibrosis: A Pilot Study. Benlala I, Hocke F, Macey J, Bui S, Berger P, Laurent F, Dournes G. Radiology. Radiology. 2020 Jan;294(1):186-196
Patient-reported outcomes in patients with cystic fibrosis with a G551D mutation on ivacaftor treatment: results from a cross-sectional study. Bell SC, Mainz JG, MacGregor G, Madge S, Macey J, Fridman M, Suthoff ED, Narayanan S, Kinnman N. BMC Pulm Med. 2019 Aug 13;19(1):146
Automated Volumetric Quantification of Emphysema Severity by Using Ultrashort Echo Time MRI: Validation in Participants with Chronic Obstructive Pulmonary Disease. Benlala I, Berger P, Girodet PO, Dromer C, Macey J, Laurent F, Dournes G. Radiology. 2019 Jul;292(1):216-225
CT evaluation of hyperattenuating mucus to diagnose allergic bronchopulmonary aspergillosis in the special condition of cystic fibrosis. Refait J, Macey J, Bui S, Fayon M, Berger P, Delhaes L, Laurent F, Dournes G. J Cyst Fibros. 2019 Jul;18(4):e31-e36

Autres

2013 « La mucoviscidose de l'adulte aux urgences » of book « Maladies rares en médecine d'urgence » Springer Edition
2011 and 2012 Mission of European Respiratory Society Congress for the French Pulmonology Society (Société de Pneumologie de Langue Française)
2009 « Maladies infectieuses et transmissibles » Cahiers des ECN collection, Elsevier Masson Edition
2007 Creation of the Young Pulmonologist Association of Paris Ile-de-France (AJPO2 Paris)
Member of SPLF (Société de Pneumologie de Langue Françaises), ECFS (European Cystic Fibrosis Society) and SFM (Société Française de la Mucoviscidose)